Preparation of functional human factor VIII
AssigneeGenentech, Inc.
InventorsWilliam I. Wood, Daniel J. Capon, Richard M. Lawn, Gordon A. Vehar
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Abstract
Functional human factor VIII produced recombinantly is used in the treatment of human beings diagnosed to be deficient in factor VIII coagulant activity. Also provided are DNA isolates and expression vehicles encoding functional human factor VIII, as well as transformed host cells and processes for producing human factor VIII by use of recombinant DNA technology.
Claims6
Isolated DNA comprising a sequence encoding functional human factor VIII.
The vector pAML3P.8c1.
A process for producing factor VIII which comprises transforming a host cell with DNA encoding functional human factor VIII and culturing the host cell under conditions that produce factor VIII.
Dependencies are inferred from the claim text.