Unique lectins
AssigneeIncyte Pharmaceuticals, Inc.
InventorsGlenn Nedwin, Tim Bringman, Pierre-Olivier Couraud
Life of this patent
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Abstract
A human HL-60 lectin having an amino acid sequence different from other known animal lectins is disclosed. This is one member of a class of mammalian lectins extractable in lactose or detergent and specific for beta-D-galactosides (14-beta-gal lectin which contains at least one glycosylation site). Recombinant methods and materials for production of the mammalian 14-beta-gal lectins, especially HL-60 lectin, in a variety of hosts, and methods to utilize the resulting lectins are also described.
Claims7
A recombinant DNA molecule in isolated and purified form encoding the lectin "having the amino acid sequence of from positions 2-135 as set forth in FIG. 1A".
Dependencies are inferred from the claim text.