Combination chemotherapy
AssigneeSmithKline Beecham Corporation
InventorRandall K. Johnson
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Abstract
A pharmaceutical composition comprising a compound of the camptothecin analog class and a platinum coordination compound and a pharmaceutically acceptable carrier or diluent; a method of inhibiting the growth of tumor cells in a human afflicted therewith which comprises administering to such human an effective tumor cell growth inhibiting amount of such pharmaceutical composition; and a method of inhibiting the growth of tumor cells in a human afflicated therewith which comprises administering to such human an effective tumor cell growth inhibiting amount of the combination of a compound of the camptothecin analog class and a platinum coordination compound.
Claims8
A method of inhibiting the growth of tumor cells sensitive to a synergistic effective amount of topotecan in combination with a synergistic effective amount of cisplatin, in a human afflicted therewith, which comprises administering to such human an effective amount of topotecan in combination with an effective amount of cisplatin sufficient to achieve synergistic tumor growth inhibition.
A pharmaceutical composition comprising a synergistic effective amount of topotecan, a synergistic effective amount of cisplatin, and a pharmaceutically acceptable carrier or diluent.
Dependencies are inferred from the claim text.