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US 5,633,015 AGranted
Beads having a core coated with an antifungal and a polymer
OwnerPaul M. V. Gilis, Valentin F. V. De Conde +1inventors
InventorsPaul M. V. Gilis, Valentin F. V. De Conde, Roger P. G. Vandecruys
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Abstract
The present invention is concerned with beads comprising a 25-30 mesh core, a coating of a hydrophilic polymer and an antifungal agent, and a seal outer coating layer; pharmaceutical dosage forms comprising said beads and a method of preparing said beads. Preferred antifungal agents are lipophilic azole antifungals, such as itraconazole and saperconazole.
Claims18
A bead comprising:
- a) a central, rounded or spherical core;
- b) a coating film of a hydrophilic polymer and an antifungal agent selected from the group consisting of itraconazole and saperconazole, and
- c) a seal-coating polymer layer, characterized in that the core has a diameter of from about 600 to about 700 .mu.m (25-30 mesh).
Dependencies are inferred from the claim text.