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US 5,633,008 AGranted
Method of administering nicotine transdermally
OwnerJames L. Osborne, Melinda K. Nelson +4inventors
InventorsJames L. Osborne, Melinda K. Nelson, David J. Enscore, Su I. Yum, Robert M. Gale, Donna D. Causey
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Abstract
A method of administering nicotine transdermally in which a nicotine patch, capable of administering nicotine for at least 16 hours at rates that are efficacious in smoking cessation therapy, is applied in the morning upon waking and removed prior to sleep. This method is effective even though nicotine is not essential during sleep and many smokers experience morning craving.
Claims9
A method for administering nicotine to an individual in need of such administration comprising:
- a) applying to the skin of said individual upon waking, a transdermal device comprising a nicotine reservoir containing a sufficient quantity of nicotine to maintain a useful transdermal flux of nicotine from said device for a total time period of at least 16 hours;
- b) maintaining said device in nicotine transmitting relationship to the skin during waking hours;
- c) removing said device prior to sleep.
Dependencies are inferred from the claim text.