Biostable corneal implants
AssigneeAllergan, Inc.
InventorsRichard S. Graham, Crystal M. Cunanan
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Abstract
Corneal implants and methods for producing such implants are disclosed. The present corneal implants comprise a lens body which is optically clear and is structured to be surgically attached in or on the cornea of a mammalian eye, the lens body including a hydrogel composition containing water, a collagen component and a polymeric material covalently bonded to the collagen component. The hydrogel composition has enhanced biostability relative to an identical hydrogel composition without the polymeric material.
Claims13
A corneal implant comprising a lens body which is optically clear and is structured to be surgically attached in or on the cornea of a mammalian eye, said lens body including a hydrogel composition comprising water, a collagen component and a polymeric material covalently bonded to said collagen component, said polymeric material being present in an amount at least equal to the amount, by weight, of said collagen component, having increased hydrophobicity relative to said collagen component, and being derived from the polymerization of a monomeric component having a fractional polarity equal to or less than the fractional polarity of methyl methacrylate, and said hydrogel composition having enhanced biostability relative to an identical hydrogel composition without said polymeric material.
A corneal implant comprising a lens body which is optically clear and is structured to be surgically attached in or on the cornea of a mammalian eye, said lens body including a hydrogel composition comprising water, a collagen component and a polymeric material covalently bonded to said collagen component, said polymeric material having increased hydrophobicity relative to said collagen component and being derived from a monomeric component having a fractional polarity equal to or less than the fractional polarity of methyl methacrylate, said hydrogel composition having enhanced biostability relative to an identical hydrogel composition without said polymeric material.
Dependencies are inferred from the claim text.