Markers for use in screening patients for nervous system dysfunction and a method and apparatus for using same
OwnerDavid Eidelberg, James R. Moellerinventors
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Abstract
A method and apparatus for screening patients for nervous system dysfunction including neurological capacity and dysfunction. A patient profile of actual functional activity of a brain of a patient is produced and compared with at least one marker. The marker is a profile of predetermined functional activity at a plurality of sets of predetermined coordinates of a given brain geometry.
Claims26
A method for screening patients for nervous system dysfunction, comprising the steps of:
- producing a patient profile of actual functional activity of a brain of a patient;
- and comparing the patient profile with at least one marker comprising a profile of predetermined functional activity at a plurality of sets of predetermined coordinates of a given brain geometry.
An apparatus for determining the presence or severity of nervous system dysfunction in a patient, comprising:
- a memory storing at least one marker for a nervous system dysfunction, the at least one marker comprising a profile of predetermined functional activity at a plurality of sets of predetermined coordinates of a given brain geometry;
- a pre-processor receptive of data corresponding to functional activity of a brain of a patient for producing a patient profile of functional activity for each of a plurality of regions of interest of the patient's brain corresponding to the plurality of sets of predetermined coordinates of the given brain geometry;
- a processor for cross-correlating the patient profile with the at least one marker;
- and a post-processor for determining at least one of a presence and severity of the nervous system dysfunction as a function of a degree of covariance for the cross-correlation.
A method for determining at least one of a presence and severity of nervous system dysfunction in a patient, comprising the steps of providing at least one marker for a nervous system dysfunction, the at least one marker comprising a profile of predetermined functional activity at a plurality of sets of predetermined coordinates of a given brain geometry;
- producing a patient profile of functional activity for each of a plurality of regions of interest of a patient's brain corresponding to the plurality of sets of predetermined coordinates of the given brain geometry;
- cross-correlating the patient profile with the at least one marker;
- and determining at least one of a presence and severity of the nervous system dysfunction as a function of a degree of covariance for the cross-correlation.
Dependencies are inferred from the claim text.