Back to results
US 5,631,384 AGranted
Areno [e]indols, preparation method and application as intermediates in the synthesis of products with antitumoral activity
AssigneePharma-Mar, S.A.- Pharmar
InventorsKoen Alexander, Jose Delamano Garcia, Benedikt Sas, Gabriel Tojo Suarez, Dolores Garcia Gravalos
Life of this patent
Estimating the term…
Abstract
The compounds (I) are useful as intermediates in the synthesis of hexahydroareno(e)cyclopropa(c)indol-4-ones with antitumoral activity.
Claims4
New areno[e]indols useful as intermediates in the synthesis of products with antitumor activity of formula:
- ##STR9## wherein:
- --Ar represents phenyl or substituted phenyl
- --Ar' represents a condensed radical of formulae:
- ##STR10## wherein R, R.sup.1, R.sup.2, R.sup.3 can represent a hydrogen, a halogen, a linear or branched alkyl, alkenyl or alkynyl radical, a formyl, acyl, carboxy, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, cyano, hydroxy, alkoxy, amino, alkylamino, dialkylamino, acylamino or nitro radical;
- and X represents oxygen, sulfur or substituted or unsubstituted nitrogen.
2 more elements
Dependencies are inferred from the claim text.