Substituted benzenesulfonylureas and -thioureas, preparation processes and possible uses of pharmaceutical preparations based on these compounds

A substitued benzenesulfonylurea or -thiourea of the formula I ##STR30## In which:

• R(1) is hydrogen, (C.sub.1 -C.sub.6)-alkyl, (C.sub.3 -C.sub.6)-cycloalkyl, C.sub.a H.sub.2a -(C.sub.3 -C.sub.5)-cycloalkyl, (C.sub.3 -C.sub.6)-alkenyl or C.sub.c H.sub.2c --C.sub.d F.sub.2d+1 ;
• a is 0, 1, 2, or 3;
• c is 0, 1, 2, or 3;
• d is 1, 2, 3, 4. 5, or 6;
• R(2) is hydrogen, F,CI, Br, I, (C.sub.1 -C.sub.6)-alkyl, (C.sub.1 -C.sub.6)-alkoxy, (C.sub.1 -C.sub.6)-mercaptoalkyl, (C.sub.1 -C.sub.6)-fluoroalkoxy, O--C.sub.e H.sub.2e --C.sub.f F.sub.2f+1, (C.sub.1 -C.sub.6)-fluoroalkyl, C.sub.g H.sub.2g --C.sub.h F.sub.2h+1, (C.sub.3 -C.sub.6)-cycloalkyl or NR(4)R(5);
• e is 0, 1, 2, or 3;
• f is 1, 2, 3, 4, 5. or 6
• g is 0, 1, 2, or 3;
• h is 1, 2, 3, 4, 5 or 6;
• R(4) and R(5) together are a (CH.sub.2).sub.4 chain;
• or
• R(4) and R(5) independently of one another are hydrogen, (C.sub.1 -C.sub.6)-alkyl, C.sub.k H.sub.2k --C.sub.m F.sub.2m+1, (C.sub.3 -C.sub.6)-cycloalkyl, (C.sub.1 -C.sub.2)-alkyl-(C.sub.3 -C.sub.5)-cycloalkyl or (C.sub.3 -C.sub.6)-alkenyl;
• k is 0, 1, 2, or 3;
• m is 1, 2, 3, 4, 5 or 6;
• E is oxygen or sulfur;
• Y is a hydrocarbon chain --{CR(7).sub.2 }.sub.n --
• R(7) is H or (C.sub.1 -C.sub.2)-alkyl;
• n is 1, 2, 3, or 4;
• R(3) is a substituted heterocyclic radical of the formula ##STR31## B is C.sub.3 alkenyl, which is unsubstituted or substituted by up to 3 (C.sub.1 -C.sub.4)-alkyl groups or by a phenyl radical.