US 5,631,270 A · Substituted pyridinylamino-1H-indoles, 1H-indazoles, 2H-indazoles, benzo [b ]

Abstract

This invention relates to substituted pyridinylamino-1H-indoles, 1H-indazoles, 2H-indazoles, benzo[b]thiophenes and 1,2-benzisothiazoles of the formula ##STR1## wherein Q is S, N or NR.sub.2 ; Y is CH, N or NR.sub.2 ; R.sub.1 is hydrogen, loweralkyl, loweralkynyl, loweralkenyl, arylloweralkyl, loweralkoxycarbonylaminoloweralkylcarbonyl, arylloweralkoxycarbonylaminoloweralkylcarbonyl, aminoloweralkylcarbonyl, loweralkoxycarbonyl or acyl; R.sub.2 is hydrogen or loweralkyl; R.sub.3 is hydrogen or loweralkyl; X is hydrogen, loweralkyl, halogen; and n is 0 or 1; or a pharmaceutically acceptable acid addition salt thereof that are useful in the treatment of memory dysfunctions.

Claims1

Dependent claims

A method of treating a patient in need of relief from a memory dysfunction which comprises administering to said patient an effective amount of compound of the formula ##STR17## wherein Q is S, N or NR.sub.2 ;

Y is CH, N or NR.sub.2 ;
R.sub.1 is hydrogen, loweralkyl, loweralkynyl, loweralkenyl, arylloweralkyl, loweralkoxycarbonylaminoloweralkylcarbonyl, arylloweralkoxycarbonylaminoloweralkylcarbonyl, aminoloweralkylcarbonyl, loweralkoxycarbonyl or acyl;
R.sub.2 is hydrogen or loweralkyl;
R.sub.3 is hydrogen or loweralkyl;
X is hydrogen, loweralkyl or halogen;
and
n is 0 or 1;
or a pharmaceutically acceptable acid addition salt thereof.

5 more elements

Dependencies are inferred from the claim text.

Facts

Application

08/464,994Filed 5 Jun 1995 · division

Priority

23 Sep 1991

Granted

20 May 1997

Term ends

Not estimatedThe source records don’t support an estimate.

Classification4 codes

C07D 401/12
Containing two hetero rings: linked by a chain containing hetero atoms as chain links
C07D 409/12
Containing two hetero rings: linked by a chain containing hetero atoms as chain links
C07D 417/12
Containing two hetero rings: linked by a chain containing hetero atoms as chain links
C07D
Heterocyclic compounds

Family

Serial764,031Parent of this division · filed 23 Sep 1991

Serial925,822Parent of this division · filed 7 Aug 1992

Serial38,427Parent of this division · filed 25 Mar 1993

US 5,424,322 AParent of this division

US 5,246,947 AParent of this division

US 5,185,350 AParent of this division

US 5,631,270 AThis patent

From the US filing history. Foreign family members aren’t listed.

Substituted pyridinylamino-1H-indoles, 1H-indazoles, 2H-indazoles, benzo [b ]

Life of this patent

Substituted pyridinylamino-1H-indoles, 1H-indazoles, 2H-indazoles, benzo [b ]

Life of this patent

Abstract

Claims1