Method for the determination of specific gravity of fluids
AssigneeBayer Aktiengesellschaft
InventorsMichael J. Pugia, Rena A. Ide
Life of this patent
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Abstract
Disclosed are a method and device for the determination of specific gravity in aqueous systems, particularly urine. The invention improves upon the known systems for detecting specific gravity by the use of a polyelectrolyte polymer and pH indicator by the addition of a crown ether ionophore which enhances the ability of the reagent system to indicate the fluid's specific gravity.
Claims12
In a method for determining the specific gravity of a fluid test sample which method comprises combining the test sample with an acidic or basic polyelectrolyte polymer which is at least about 50 percent neutralized and a pH indicator capable of producing a detectable response based on interaction between the polyelectrolyte and the fluid test sample, the improvement which comprises introducing a crown ether ionophore into the combination of fluid sample, polymer and indicator.
A test device for the determination of the specific gravity of a fluid test sample which comprises an absorbant carrier having absorbed therein an acidic or basic polyelectrolyte polymer which is at least about 50 percent neutralized, a pH indicator capable of producing a detectable response based on interaction between the polyelectrolyte polymer and the fluid test sample and a crown ether ionophore.
A test strip for the determination of the specific gravity of urine which comprises filter paper having absorbed therein a maleic anhydride/methylvinylether polyelectrolyte which is at least about 50 percent neutralized, bromo thyoml blue and a crown ether ionophore selected from the group consisting of dibenzo-16-crown-5-oxyacetic acid, dicyclohexano-16-crown-5-oxyacetic acid and naptho-15-crown-5.
Dependencies are inferred from the claim text.