Low sodium peritoneal dialysis solution
AssigneeBaxter International Inc.
InventorsTy R. Shockley, Leo Martis, Lee W. Henderson, John Moran, Masaaki Nakayama
Life of this patent
Estimating the term…
Abstract
An improved peritoneal dialysis solution and methods of administering same to a patient are provided. Pursuant to the present invention, the sodium concentration in the solution is decreased thus causing sodium to be transported from the circulation to the peritoneal cavity. This provides for an improved ultrafiltration profile for the same initial osmolality when compared to standard solutions. Also, the same ultrafiltration profile as standard solutions can be achieved with lower initial osmolalities.
Claims10
A peritoneal dialysis solution For providing a sustained osmotic gradient comprising:
- an osmotic agent including at least one polypeptide;
- and
- sodium in a concentration that is less than a sodium plasma concentration in a renal patient who is to receive the solution.
A method for providing peritoneal dialysis to a patient comprising the step of administering a solution including sodium and an osmotic agent including at least one polypeptide to a patient, the sodium level being less than a plasma sodium concentration of the patient.
A method for allowing increased salt intake in a diet of a dialysis patient comprising the step of administering to the dialysis patient a peritoneal dialysis solution comprising an osmotic agent that includes at least one polypeptide and sodium in a concentration that is less than a sodium concentration in the dialysis patient who is to receive the solution.
Dependencies are inferred from the claim text.