2-(arylimino-methyl)-3-dialkylaminoacrylonitriles, a process for their preparation and their use
AssigneeBayer Aktiengesellschaft
InventorsHelmut Kraus, Horst Behre, Helmut Fiege
Life of this patent
Estimating the term…
Abstract
2-(Arylimino-methyl)-3-dialkylaminoacrylonitriles can be obtained by reaction of .beta.-anilino-acrylonitriles with ortho-formamides. They are suitable as starting substances for the preparation of 4-amino-5-iminiummethylene-2-pyrimidines or 4-amino-5-formyl-2-pyrimidines.
Claims7
A process for the preparation of a compound of the formula ##STR7## wherein R.sup.1 and R.sup.2 independently of one another denote linear or branched C.sub.1 -C.sub.8 -alkyl, C.sub.2 -C.sub.8 -alkenyl, C.sub.2 -C.sub.8 -alkoxyalkyl, C.sub.3 -C.sub.8 -alkoxyalkenyl, C.sub.3 -C.sub.8 -cycloalkyl, C.sub.7 -C.sub.10 -aralkyl, C.sub.6 -C.sub.12 -aryl or a 5- to 8-membered saturated or unsaturated heterocyclic ring having 1 to 2 heteroatoms from the series consisting of N, O and S, or
- R.sup.1 and R.sup.2, together with the nitrogen atom on which they are located, denote a 5- to 8-membered ring which may contain a further heteroatom from the series consisting of N, O and S and
- R.sup.3 to R.sup.7 independently of one another denote hydrogen, linear or branched C.sub.1 -C.sub.8 -alkyl, C.sub.1 -C.sub.6 -alkoxy, C.sub.1 -C.sub.6 -alkylthio, C.sub.2 -C.sub.6 -alkenyl, C.sub.2 -C.sub.6 -alkoxyalkyl, C.sub.3 -C.sub.8 -cycloalkyl, halogen, or di-C.sub.1 -C.sub.6 -alkylamino,
- by the reaction of a compound of the formula ##STR8## wherein R.sup.3 and R.sup.7 have the above meaning,
- with a compound of the formula ##STR9## wherein R.sup.1 and R.sup.2 have the above meaning and
- A and B independently of one another denote OR.sup.8, OR.sup.9, NR.sup.10 R.sup.11 or NR.sup.12 R.sup.13, wherein the substituents R.sup.8 to R.sup.13 independently of one another have the meaning defined above for R.sup.1 and R.sup.2,
- in a molar ratio of II/III of 0.5 to 20, at a temperature of 0.degree. to 200.degree. C.
A compound of the formula ##STR10## wherein R.sup.1 and R.sup.2 independently of one another denote linear or branched C.sub.1 -C.sub.8 -alkyl, C.sub.2 -C.sub.8 -alkenyl, C.sub.2 -C.sub.8 -alkoxyalkyl, C.sub.3 -C.sub.8 -alkoxyalkenyl, C.sub.3 -C.sub.8 -cycloalkyl, C.sub.7 -C.sub.10 -aralkyl, C.sub.6 -C.sub.12 -aryl or a 5- to 8-membered saturated or unsaturated heterocyclic ring having 1 to 2 heteroatoms from the series consisting of N, O and S, or
- R.sup.1 and R.sup.2, together with the nitrogen atom on which they are located, denote a 5- to 8-membered ring which may contain a further heteroatom from the series consisting of N, O and S and
- R.sup.3 to R.sup.7 independently of one another denote hydrogen, linear or branched C.sub.1 -C.sub.8 -alkyl, C.sub.1 -C.sub.6 -alkoxy, C.sub.1 -C.sub.6 -alkylthio, C.sub.2 -C.sub.8 -alkenyl, C.sub.2 -C.sub.8 -alkoxyalkyl, C.sub.3 -C.sub.6 -cycloalkyl, halogen, or di-C.sub.1 -C.sub.6 -alkylamino.
Dependencies are inferred from the claim text.