Urea opthalmic ointment and solution
AssigneeWest Virginia University Research Corporation
InventorsJudie P. Charlton, Ivan R. Schwab
Life of this patent
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Abstract
A topical ophthalmic preparation utilizing a urea and/or urea derivative or mixtures thereof as the principle active ingredient within a range of about 0.01% by weight to about 30% by weight and a method of using the same. When applied to a mammalian eye affected with an abnormal ophthalmological surface problem resulting in epithelial cell loss, keratinization, and/or scarring, the present invention will heal epithelial defects, soften keratin, decrease scarring, enhance hydration, and have anti-mucolytic activity. The present invention provides a method for treating ocular conditions such as dryness, noninfectious keratitis, corneal or conjunctival epithelial irregularities, ocular scarring and subjective irritations.
Claims9
A method for promoting epithelialization, promoting hydration, decreasing fibroblast action and softening keratin, the method comprising the steps of:
- applying to the ocular surface of a mammalian eye an ophthalmic ointment comprising urea and/or urea derivatives or mixtures thereof.
A method for promoting epithelialization, promoting hydration, decreasing fibroblast action and softening keratin, the method comprising the steps of:
- applying to the ocular surface of a mammalian eye an ophthalmic preparation comprising a urea derivative or mixtures of urea derivatives.
A method for treating ocular conditions selected from the group consisting of ocular scarring, and subjective irritations, the method comprising the steps of:
- topical ocular application of a hyperosmolar preparation utilizing a urea derivative or mixtures of urea derivatives.
Dependencies are inferred from the claim text.