Methods for treating asthma using optically pure (-)-zileuton
AssigneeSepracor Inc.
InventorNancy M. Gray
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Abstract
Methods are disclosed utilizing optically pure (-)-zileuton for the treatment of asthma in humans while substantially reducing the concomitant liability of adverse effects associated with the racemic mixture of zileuton.
Claims8
A method of treating asthma in a human which comprises administering to said human an amount of (-)-zileuton, or a pharmaceutically acceptable salt thereof, substantially free of its (+) stereoisomer, said amount being sufficient to alleviate said asthma.
A method of treating asthma in a human while substantially reducing the concomitant liability of adverse effects associated with racemic zileuton which comprises administering to a human in need of such antiasthmatic therapy an amount of (-)-zileuton, or a pharmaceutically acceptable salt thereof, substantially free of its (+) stereoisomer, said amount being sufficient to alleviate said asthma but insufficient to cause said adverse effects.
Dependencies are inferred from the claim text.