Methods for treating gastro-esophageal reflux disease and other disorders associated with the digestive tract using optically pure (+) cisapride
AssigneeSepracor Inc.
InventorsNancy M. Gray, James W. Young
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Abstract
Methods are disclosed utilizing the optically pure (+) isomer of cisapride. This compound is useful in treating emesis while substantially reducing adverse effects associated with racemic cisapride.
Claims10
A method of eliciting an antiemetic effect in a human, comprising administering to said human a therapeutically effective amount of (+) cisapride, or a pharmaceutically acceptable salt thereof, substantially free of its (-) stereoisomer.
A method of eliciting an antiemetic effect in a human while achieving a higher bioavailability than is attainable with racemic cisapride, comprising administering to said human a therapeutically effective amount of (+) cisapride, or a pharmaceutically acceptable salt thereof, substantially free of its (-) stereoisomer.
Dependencies are inferred from the claim text.