Depot formulations
AssigneeUniversity College London
InventorsRobert Brown, Gordon Blun
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Abstract
A depot formulation comprising fibronectin or a fragment thereof, a growth factor binding agent linked thereto and growth factor bound to the binding agent is used to promote wound healing in combination with macroscopically oriented cell adhesion proteins, the depot formulations allow the healing process to be directed to afford stronger or more cosmetically acceptable results.
Claims14
A formulation comprising fibronectin or a fragment thereof, which comprises a gelatin-binding domain or a heparin-binding domain of fibronectin, the fibronectin or fragment thereof having a growth factor binding agent immobilized thereon and a growth factor releasably bound to the binding agent, and wherein the fibrils of the fibronectin or fragment thereof are in the form of a porous macroscopically oriented material.
Dependencies are inferred from the claim text.