Method for identifying individuals suffering from a cellular abnormality some of whose abnormal cells present complexes of HLA-C-clone 10/MAGE-1 derived peptides, and methods for treating said individuals

Method for determining cancer in a subject having malignant cells which present complexes of HLA-C clone 10 and MAGE-1 derived peptides on their surfaces, comprising contacting a CTL containing sample taken from a subject suspected of having cancer with cells which express both (i) molecules of HLA-C clone 10 and (ii) molecules of MAGE-1, and determining at least one of proliferation of cytolytic T cells in said CTL containing sample or lysis of said cells which express both (i) molecules of HLA-C clone 10 and (ii) molecules of a MAGE-1 gene to determine presence of cytolytic T cells which specifically bind complexes of HLA-C clone 10 and a MAGE-1 derived peptide as a determination that said subject has cancer.