Micellar nanoparticles
AssigneeNovavax, Inc.
InventorD. Craig Wright
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Abstract
The present invention relates to micellar nanoparticles and methods of their production. Micellar nanoparticles are made by hydrating a mixture of an oil, a stabilizer/surfactant, and an alcoholic initiator with an aqueous solution. These micellar nanoparticles are normally less than 100 nanometers in diameter. The micellar nanoparticles are particularly advantageous in delivering materials such as estradiol topically through the skin because their small size allows easy penetration.
Claims12
A micellar nanoparticle having a diameter of between about 25 and 1000 nm, said micellar nanoparticle comprising a lipophilic phase which includes an oil, a stabilizer and an alcohol-based initiator, hydrated with a suitable aqueous solution
- wherein said stabilizer is selected from the group consisting of Tween 60, Tween 80, nonylphenol polyethylene glycol ethers, and mixtures thereof.
Dependencies are inferred from the claim text.