Squid magnetometry using paramagnetic metal chelates
AssigneeNycomed Imaging AS
InventorsJo Klaveness, Thorfinn Ege, Scott M. Rocklage
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Abstract
The present invention relates to the use of paramagnetic materials, such as lanthanide chelates, as contrast agents in magnetometric analysis, especially imaging. The invention is particularly directed to structural and functional diagnosis or imaging.
Claims34
A method of generating a magnetometric image of a human or non-human animal body comprising administering to said body a physiologically tolerable paramagnetic metal chelate and generating a magnetometric signal of at least part of said body into which said chelate distributes.
A process for detecting variations in magnetic susceptibility within a human or non-human animal body, comprising administering to said body a physiologically tolerable paramagnetic metal chelate, and with a magnetometer continuously or repeatedly monitoring the magnetic susceptibility of at least a part of said body into which said chelate distributes.
A method of generating a magnetometric image of a human or non-human animal body comprising administering to said body a physiologically tolerable paramagnetic manganese compound and generating a magnetometric signal of at least part of said body into which said compound distributes.
A process for detecting variations in magnetic susceptibility within a human or non-human animal body, comprising administering to said body a physiologically tolerable paramagnetic manganese compound, and with a magnetometer continuously or repeatedly monitoring the magnetic susceptibility of at least a part of said body into which said compound distributes.
Dependencies are inferred from the claim text.