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US 5,628,727 AGranted
Extracorporeal virioncidal apparatus
OwnerSaid I. Hakky, A-Hamid Hakki +1inventors
InventorsSaid I. Hakky, A-Hamid Hakki, Perry B. Hudson
Life of this patent
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Abstract
An extracorporeal radiation-therapy apparatus for use in treating the blood of a donor for diseased cells or organisms. The apparatus separates the blood by a density gradient device and treats the different blood fractions with drugs and/or high energy radiation.
Claims16
An extracorporeal radiation-therapy apparatus for use in treating the blood of a donor for diseased cells or organisms capable of division comprising:
- a. means for removing a flow of blood from donor;
- b. a housing comprising;
- a first fluid communication means for receiving said blood and subjecting said blood to a density gradient device whereby blood fractions selected from plasma, white blood cells and platelets are separated;
- a second, third and fourth fluid condition means for transferring each separated blood fraction to individual treatment chambers;
- each said treatment chambers having side walls impenetrable to high energy electromagnetic radiation so as to inactivate said diseased cells or organisms, a high energy electromagnetic radiation source and at least one module treating chamber having side walls substantially transparent to said radiation and containing a semi-permeable membrane;
- said at least one module includes a fifth fluid communication means to supply a continuous flow of a complexing agent for viral particles into said module and returning said unreacted complexing agent to a complexing agent reservoir;
- said high energy electromagnetic radiation source being of an effective wavelength and intensity to inactive said diseased cells or organisms capable of division and being directed to impinge upon said at least one module to provide an irradiated filtrate;
- a third fluid communication means for receiving said irradiated filtrate substantially free of diseased cells from each of said modules and combining the irradiated filtrates of each fraction to produce recombined blood;
- and
- c. means for returning said recombined blood to the donor.
7 more elements
Dependencies are inferred from the claim text.