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US 5,627,212 AGranted
Esters of L-carnitine and acyl L-carnitine with hydoxy acids for producing pharmcaeutical compositions for treating dermatoses
AssigneeAvantgarde S.p.A.
InventorsClaudio Cavazza, Paolo Cavazza
Life of this patent
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Abstract
Dermatosis is treated by a method comprising topically applying an effective amount of an ester of L-carnitine or an acyl L-carnitine with a hydroxy carboxylic acid selected from the group consisting of .alpha.-hydroxybutyric acid, .alpha.-hydroxyisocaproic acid, .alpha.-hydroxyisovaleric acid, malic acid and tartronic acid, to a patient in need thereof.
Claims10
A method of treating dermatosis comprising:
- topically applying an effective amount of an ester of L-carnitine or an acyl L-carnitine with a hydroxy carboxylic acid selected from the group consisting of .alpha.-hydroxybutyric acid, .alpha.-hydroxyisocaproic acid, .alpha.-hydroxyisovaleric acid, malic acid and tartronic acid, said acyl group being a C.sub.1-5 alkanoyl radical selected from the group consisting of acetyl, propionyl, butyryl, isobutyryl, valeryl and isovaleryl, and the pharmaceutically acceptable salts of said esters, to a patient in need thereof.
A pharmaceutical composition for topical administration in the treatment of dermatosis, which comprises:
- an ester of L-carnitine or acyl L-carnitine with a hydroxy carboxylic acid selected from the group consisting of .alpha.-hydroxyisocaproic acid, .alpha.-hydroxyisovaleric acid, malic acid and tartronic acid, said acyl group being a C.sub.1-5 alkanoyl selected from the group consisting of acetyl, propionyl, butyryl, isobutyryl, valeryl and isovaleryl, and the pharmaceutically acceptable salts thereof in combination with a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.