Branched combinatorial libraries
AssigneeChiron Corporation
InventorsRobert Valerio, Jian-Xin Wang
Life of this patent
Estimating the term…
Abstract
Combinatorial libraries comprising compounds of the formula ##STR1## where R.sub.1, R.sub.2, and R.sub.3 are each independently groups of the formula --C(O)R, where R is an organic radical; x, y, and z are each independently 1, 2, 3, or 4; R.sub.4 is alkyl, alkenyl, aryl, aralkyl, acyl, amino, hydroxy, alkoxy, aryloxy, arylalkoxy, heterocyclyl, or H, or is a solid support; and R.sub.5 is alkyl, alkenyl, aryl, aralkyl, acyl, amino, hydroxy, alkoxy, aryloxy, arylalkoxy, heterocyclyl, or H are disclosed.
Claims6
A compound of the formula:
- ##STR6## where R.sub.1, R.sub.2, and R.sub.3 are each independently groups of the formula --C(O)R, where
- R is an organic radical;
- x, y, and z are each independently 1, 2, 3, or 4;
- R.sub.4 and R.sub.5 are each independently alkyl, alkenyl, aryl, aralkyl, acyl, amino, hydroxy, alkoxy, aryloxy, aryl-alkoxy, heterocyclyl, or H.
A compound of the formula ##STR7## and pharmaceutically acceptable salts thereof.
A composition for treating a uPA-mediated disorder, said composition comprising:
- a compound of the formula ##STR8## or a pharmaceutically acceptable salt thereof;
- and a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.