Methods and means for control of proliferation of remnant cells following surgery
OwnerArlene E. Gwon, Charles J. Hagemeierinventors
Life of this patent
Estimating the term…
Abstract
The present invention relates to methods to control undesired cell proliferation of remnant cells following surgery, by applying an effective amount of at least one proteoglycan-type substrate adhesion molecule (SAM) to the site of surgery. SAMs, in particular chondroitin sulfate, hyaluronic acid, and non-toxic, pharmaceutically acceptable salts thereof, alone or in a composition form, are typically used to prevent or inhibit growth of lens-related cells in a lens capsule after surgical removal of the lens, or to prevent proliferative vitreoretinopathy following retinal reattachment procedure performed with or without vitrectomy.
Claims10
A method for control of the proliferation of remnant epithelial cells in a remaining lens capsular bag structure following removal of the natural lens, comprising applying an effective amount of a mixture of chondroitin sulfate and hyaluronic acid directly into the remaining lens capsular bag structure.
A method for the control of the proliferation of remnant epithelial cells in a remaining lens capsular bag structure following removal of the natural lens comprising applying a mixture of from 1 to 10 percent of chondroitin sulfate and 1 to 3 percent hyaluronic acid, w/v, into the remaining lens capsular bag structure.
Dependencies are inferred from the claim text.