Ascorbic acid compositions providing enhanced human immune system activity
AssigneeMetagenics, Inc.
InventorStephen M. Paul
Life of this patent
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Abstract
A vitamin C supplement comprising ascorbic acid, ascorbyl palmitate, niacinamide ascorbate, calcium ascorbate, magnesium ascorbate, potassium ascorbate, and sodium ascorbate which together can be administered to a human to avoid the transitory initial suppression of human NK cell activity which is present when ascorbic acid alone is administered. Also included is xylitol, lysine acetate, tetrasodium pyrophosphate, ribose, cysteine, and hesperidin which further prolongs the biological activity of ascorbic acid and promotes the uptake of ascorbic acid by human tissue.
Claims34
A dietary ascorbic acid supplement composition providing enhanced human immune system activity with substantially no post administration transient suppression of human NK immune cell activity, the ascorbic acid supplement comprising:
- a water soluble form of ascorbic acid selected from the group consisting of ascorbic acid, biologically acceptable mineral salts of ascorbic acid, niacinamide ascorbate and mixtures thereof;
- a fat soluble ascorbyl ester selected from the group consisting of ascorbyl palmitate, ascorbyl arachidonate, ascorbyl stearate, ascorbyl linoleate, ascorbyl linoleneate, ascorbyl oleate, ascorbyl acetate, ascorbyl butyrate, and mixtures thereof, wherein the weight ratio between said water soluble form of ascorbic acid and said fat soluble ascorbyl ester is between about 50:1 and about 5:1;
- and
- at least one ascorbic acid metabolite selected from the group consisting of basic amino acids, metabolic by-products of ascorbic acid breakdown, flavonoid, sulfur containing amino acids, tetrasodium pyrophosphate, and glutathione.
A method of administering ascorbic acid to a human with substantially no post administration transient suppression of human NK immune cell activity which comprises administering to a human an effective amount of a composition comprising:
- a water soluble form of ascorbic acid selected from the group consisting of ascorbic acid, biologically acceptable mineral salts of ascorbic acid, niacinamide ascorbate and mixtures thereof;
- and
- selected from the group consisting of ascorbyl palmitate, ascorbyl arachidonate, ascorbyl stearate, ascorbyl linoleate, ascorbyl linoleneate, ascorbyl oleate, ascorbyl acetate, ascorbyl butyrate, and mixtures thereof, wherein the weight ratio between said water soluble form of ascorbic acid and said fat soluble ascorbyl ester is between about 50:1 and about 5:1.
Dependencies are inferred from the claim text.