Infusion preparation
AssigneeThe Green Cross Corporation
InventorsTadaaki Inoue, Hideto Kodaira, Yoshihito Nawa, Ryoichiro Murashima, Shunichi Abe, Kazumasa Yokoyama
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AssigneeThe Green Cross Corporation
InventorsTadaaki Inoue, Hideto Kodaira, Yoshihito Nawa, Ryoichiro Murashima, Shunichi Abe, Kazumasa Yokoyama
Estimating the term…
Disclosed is an infusion preparation for nutrient supply use. It comprises a sugar, amino acids, electrolytes and a fat emulsion. It has an excellent shelf life without causing precipitation, denaturation and the like in spite of the simultaneous presence of these components. Also disclosed is a container filled with infusion liquids comprising a first and a second compartments separated from each other by a separation means, wherein an infusion liquid containing a fat emulsion and a sugar is included in the first compartment and another infusion liquid containing amino acids and electrolytes is included in the second compartment. Further disclosed are an infusion preparation comprising a fat emulsion and a sugar, and an infusion preparation comprising amino acids and electrolytes. An infusion preparation containing a sugar, amino acids, electrolytes and a fat emulsion can be obtained easily and aseptically upon use, by simply removing a separation means attached to the container and mixing the two infusion liquids.
A process for producing an infusion preparation comprising an infusion liquid containing a nutrient-supplying fat emulsion having a mean particle size of 0.17 .mu.m or less which comprises emulsifying a fat using an emulsifying agent together with one or more compounds present during the emulsification and selected from the group consisting of glycerol and glucose.
A process for preventing fat particle aggregation in an infusion fat emulsion which comprises mixing an infusion fat emulsion with a solution containing divalent metal ions in the presence of at least one organic acid selected from the group consisting of citric acid, lactic acid, malic acid, gluconic acid, maleic acid and malonic acid and salts thereof, whereby aggregation of fat particles of the fat emulsion is prevented.
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