Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx
AssigneeThe Procter & Gamble Company
InventorPaul F. Cavanaugh, Jr.
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Abstract
The present invention provides novel methods for prevention or treatment of primary and recurring squamous cell carcinoma of the oral cavity or oropharynx comprising topical administration, to the oral cavity or oropharynx, of an effective amount of an NSAID, especially a composition administering from about 0.001% to about 0.2% ketorolac to the oral cavity, alone or as an adjunct to surgery and/or radiation therapy.
Claims8
A method of treatment for primary and recurring squamous cell carcinoma of the oral cavity or oropharynx of a human or mammal having said carcinoma, comprising the topical administration to the oral cavity or oropharynx of said human or lower animal, of a composition, free of hyaluronic acid, comprising an effective amount of an NSAID, alone or as an adjunct to surgery and/or radiation therapy, wherein said composition is held in the oral cavity for a period of from about 15 seconds to about 10 minutes, then largely expectorated rather than being swallowed.
A method of treatment for primary and recurring squamous cell carcinoma of the oral cavity or oropharynx of a human or mammal having said carcinoma, comprising the topical administration to the oral cavity or oropharynx of said human or lower animal, of a composition, free of hyaluronic acid, providing from about 0.001% to about 0.2%, by weight of ketorolac to the oral cavity or oropharynx, alone or as an adjunct to surgery and/or radiation therapy, wherein said composition is held in the oral cavity for a period of from about 15 seconds to about 10 minutes. then largely expectorated rather than being swallowed.
Dependencies are inferred from the claim text.