Electroconvulsive therapy method using ICTAL EEG data as an indicator of ECT seizure adequacy
AssigneeDuke University
InventorsAndrew D. Krystal, Richard D. Weiner
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Abstract
A method in electroconvulsive therapy (ECT) to use ictal EEG data for clinical determination of the adequacy of an induced seizure in a patient. The method includes employing an ECT device to apply electricity to the patient in an ECT session to induce seizure activity. The electroencephalographic (EEG) data is detected during the seizure and selected EEG data parameters are derived therefrom. Next, the likely adequacy of the induced seizure is computed by comparing the selected EEG data parameters of the patient to ictal EEG data parameters wherein the adequacy of the corresponding seizure or seizures is known, and the computed likely therapeutic adequacy of the induced seizure is displayed.
Claims23
A method in electroconvulsive therapy (ECT) to use ictal EEG data and to compute certain parameters therefrom, wherein the EEG data is obtained from at least one seizure of a known seizure adequacy, for clinical determination of the adequacy of an induced seizure in a patient, the method comprising the steps of:
- (a) employing an ECT device to apply electricity, having a stimulus intensity, to the patient in an electroconvulsive therapy session of a course of treatment to induce seizure;
- (b) generating EEG data and to compute certain parameters therefrom by detecting the electrical brain waves of the patient during at least one of the seizure and immediate post seizure and selecting the certain EEG data parameters therefrom;
- (c) computing a likely therapeutic adequacy of the induced seizure by comparing the selected certain EEG data parameters of the patient to the ictal EEG data parameters of known seizure adequacy;
- and
- (d) displaying the computed likely therapeutic adequacy of the induced seizure.
A method in electroconvulsive therapy (ECT) to use ictal EEG data, having certain parameters obtained from at least one seizure of a known adequacy, for clinical determination of the adequacy of an induced seizure in a patient, the method comprising the steps of:
- (a) employing an ECT device to apply electricity to the patient in an electroconvulsive therapy session to induce seizure;
- (b) generating EEG data, having certain parameters, by detecting the electrical brain waves of the patient during at least one of the seizure and post seizure and selecting the certain EEG data parameters therefrom;
- (c) computing a likely therapeutic adequacy of the induced seizure with a multivariate ictal EEG model by comparing the selected certain EEG data parameters of the patient to the ictal EEG data parameters of a known seizure adequacy, wherein the ictal EEG data parameters are collected from a population of different patients during ECT induced seizures;
- and
- (d) displaying the computed likely therapeutic adequacy of the induced seizure.
A method in electroconvulsive therapy (ECT) to use ictal EEG data, having certain parameters obtained from at least one seizure of a known seizure adequacy, for clinical determination of the adequacy of an induced seizure in a patient, the method comprising the steps of:
- (a) employing an ECT device to apply electricity to the patient in an electroconvulsive therapy session of a course of treatment to induce a seizure;
- (b) generating EEG data, having certain parameters, by detecting the electrical brain waves of the patient during at least one of the seizure and post seizure and selecting the certain EEG data parameters therefrom;
- (c) computing a likely therapeutic adequacy of the induced seizure with a multivariate ictal EEG model by comparing the selected certain EEG data parameters of the patient to the ictal EEG data parameters of a known seizure adequacy, wherein the ictal EEG data parameters are collected from one or more prior ECT induced seizures of the patient during the treatment course;
- and
- (d) displaying the computed likely therapeutic adequacy of the induced seizure.
Dependencies are inferred from the claim text.