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US 5,624,677 AGranted
Controlled release of drugs delivered by sublingual or buccal administration
AssigneePentech Pharmaceuticals, Inc.
InventorsRagab El-Rashidy, Bruce Ronsen, Emad E. Hassan
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Abstract
A composition providing a relatively slow release of water-soluble drugs, such as apomorphine, for delivery via the sublingual or buccal routes.
Claims20
A composition providing a relatively slow release of water-soluble drugs by sublingual route and consisting essentially of:
- about 2 to about 10 milligrams of a water-soluble drug which is a member of the group consisting of apomorphine hydrochloride, albuterol sulfate, timolol maleate, verapamil hydrochloride, and naloxone hydrochloride, and;
- an osmotic agent;
- a swellable hydrophilic carrier;
- and a water dispersible polymer;
- the composition having a T.sub.90 value in the range of more than about 25 to about 300.
2 more elements
Dependencies are inferred from the claim text.