Dry powder inhaler delivery system
AssigneeDura Pharmaceuticals, Inc.
InventorsRobert F. Eisele, Allan Cameron, David Titzler, Leonard Porche
Life of this patent
Estimating the term…
Abstract
A powder storage and delivery system for a drug powder inhaler has a carrier disk with a blister shell sealed by a shear layer. A tab is adhered to the shear layer, underneath the blister shell. The carrier disk is placed into a dry powder inhaler. An actuator pushes against the tab, causing the shear layer to tear away, releasing the powder drug contents from the blister into the dry powder inhaler. A disk carrier has bursting blisters with a brittle blister shell sealed with a foil lid, and covered by a plate. An actuator moves against the plate, causing the plate to buckle and the blister shell to burst open, releasing powdered drug into the dry powder inhaler.
Claims26
A powder storage and delivery system for a dry powder inhaler, comprising:
- a carrier;
- a blister shell on the carrier;
- a shear layer attached around the perimeter of the blister shell;
- and
- a tab pivotably attached to the carrier and attached to the shear layer.
A powdered drug storage and delivery system comprising:
- a carrier disk;
- a tab attached to the carrier disk by a shear layer;
- and
- a blister containing a drug dose on the tab attached to the shear layer.
A powdered drug storage and delivery system comprising:
- a round carrier disk having a central opening;
- a plurality of shear tabs radially projecting from the central opening, each shear tab having a circumferential edge spaced apart from the carrier disk across a gap, and with each shear tab pivotably connected to the carrier disk at a hinge line along one side of the tab;
- a shear layer overlying, attached to, and connecting the carrier disc and the shear tabs;
- and
- a blister layer overlying and attached to the shear layer, the blister layer including a plurality of blister shells forming a powder containing space in between the shear layer and the blister shells, and with one blister shell formed on substantially each tab.
A drug storage and delivery system comprising:
- a carrier having a tab;
- a shear layer having a top surface and a bottom surface, with the bottom surface of the shear layer attached to the tab;
- a blister shell on the tab, with the blister shell having a perimeter attached to the top surface of the shear layer;
- and
- a drug contained between the top surface of the shear layer and the blister shell.
The dry powder delivery system, comprising:
- a carrier disk;
- a plurality of individual plates on the carrier disk radially spaced apart from each other;
- a plurality of brittle blister shells, with substantially one blister shell attached to each plate;
- each blister shell having a centrally located score line;
- and
- a dose of powdered drug within the blister shells.
A drug storage and delivery system comprising:
- an inhaler having a housing;
- an actuator displaceably mounted within the housing;
- and
- a carrier disk incrementally rotatable on the housing, the carrier disk including a tab attached to the carrier disk by a shear layer and a blister on the tab attached to the shear layer;
- with the actuator positioned to push on the tab and open the blister by shearing the shear layer.
A method of delivering a drug dose comprising the steps of:
- providing an inhaler having a housing and a carrier disk with a tab and an actuator within the housing, said the carrier disk having a blister including a shear layer and containing a dose of drug;
- advancing the carrier disk on the housing to a position in alignment with the actuator in the housing;
- moving the actuator to engage and displace a tab on the carrier disk;
- pivoting the tab via the actuator and shearing the shear layer sealing the dose of drug within the blister on the carrier disk;
- and
- allowing the dose of drug to fall out of the blister and into the inhaler housing.
Dependencies are inferred from the claim text.