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US 5,621,039 AGranted
Factor IX- polymeric conjugates
OwnerTerrence W. Hallahan, Carl W. Gilbertinventors
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Abstract
Conjugates containing a substance with coagulant activity, such as recombinant Factor IX, non-antigenic polymers, such as poly(ethylene glycol), are disclosed. Also disclosed are methods of forming the novel conjugates of this invention.
Claims9
A biologically active conjugate comprising a first substance having Factor IX activity bound to a substantially non-antigenic polymeric substance by a linkage containing a hydrazide or hydrazone functional group.
Dependencies are inferred from the claim text.