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US 5,616,491 AGranted
Knockout mice
AssigneesThe Ontario Cancer Institute, Craig B. Thompson
InventorsTak W. Mak, Craig B. Thompson
Life of this patent
Estimating the term…
Abstract
Mice lacking expression of CD28 or particular CD45 isoforms in certain cells of the immune system are provided. Also provided are methods of using these mice.
Claims3
A DNA construct comprising intron 1 and exon 2 of a mouse CD28 gene into which a marker sequence has been inserted.
Dependencies are inferred from the claim text.