Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
AssigneeThe Trustees of Columbia University in the City of New York
InventorsCharles L. Fox, Jr., Shanta M. Modak, Lester A. Sampath
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Abstract
A method of preparing an infection-resistant medical device comprising one or more matrix-forming polymers selected from the group consisting of biomedical polyurethane, biomedical silicones and biodegradable polymers, and antimicrobial agents, especially a synergistic combination of a silver salt and chlorhexidine (or its salts); also disclosed are medical devices having the synergistic composition therein or compositions thereon.
Claims2
A method for preparing a medical article comprising forming a layer of a polymeric material containing an antiinfective agent selected from the group consisting of a biguanide and silver sulfadiazine bulk distributed therein onto a surface of a preformed hydrophilic polymeric article.
Dependencies are inferred from the claim text.