Method for the preparation of hemodialysis fluids containing bicarbonate

A method for preparing a bicarbonate hemodialysis fluid adapted to the individual physiological requirements of a patient in need of dialysis, comprising the steps:

• i) providing a primary concentrate (a) of fixed concentration and not tailored to the individual physiological requirements of the patient,
• ii) providing a plurality of additional concentrates (b) having differing compositions,
• iii) selecting a concentrate (b) according to the individual physiological requirements of the patient, and
• iv) diluting concentrate (a) and the selected concentrate (b) with water to obtain said hemodialysis fluid;
• wherein
• primary concentrate (a) supplies sodium ions between 120 and 135 mmol/liter based on the hemodialysis fluid, 100% of the bicarbonate and has a molar ratio of bicarbonate/sodium of 0.3 or less;
• and
• concentrate (b) is a 120 to 250-fold liquid concentrate that supplies additional sodium in an amount up to 25 mmol/l, 0-5 mmol/l potassium, 0.3-2.5 mmol/l calcium and 0-1.2 mmol/l magnesium ions, all concentrations based on said hemodialysis fluid, representing the total quantities of calcium and magnesium ions in the hemodialysis fluid.