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AssigneeRhone-Poulenc Agrochimie
InventorsTerry L. Thomas, Avutu S. Reddy, Michael Nuccio, Andrew N. Nunberg, Georges L. Freyssinet
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Linoleic acid is converted into .gamma.-linolenic acid by the enzyme .DELTA.6-desaturase. The present invention is directed to isolated nucleic acids comprising the .DELTA.6-desaturase gene. More particularly, the isolated nucleic acid comprises the promoter, coding region and termination regions of the .DELTA.6-desaturase gene. The present invention provides recombinant constructions comprising the .DELTA.6-desaturase coding region in functional combination with heterologous regulatory sequences. The nucleic acids and recombinant constructions of the instant invention are useful in the production of GLA in transgenic organisms.
An isolated nucleic acid encoding a borage .DELTA.6-desaturase.
An isolated nucleic acid that codes for the amino acid sequence of SEQ ID NO:
A method of inducing or increasing production of gama linolenic acid (GLA) in a bacterium or plant deficient or lacking in or producing low levels of GLA and linoleic acid (LA) which comprises transforming said organism with an isolated nucleic acid encoding borage .DELTA.6-desaturase and an isolated nucleic acid encoding .DELTA.12-desaturase.
A method of inducing or increasing production of gamma linolenic acid (GLA) in a bacterium or plant deficient or lacking in or producing low levels of GLA and linoleic acid (LA) which comprises transforming said organism with at least one expression vector comprising an isolated nucleic acid encoding borage .DELTA.6-desaturase and an isolated nucleic acid encoding .DELTA.12-desaturase.
Dependencies are inferred from the claim text.