Double chain peptide compounds having hemoregulatory activity

A peptide compound of formula II ##STR13## wherein --A-- is a C.sub.1-6 carbon chain interrupted by one or more double or triple carbon-carbon bonds,

• R.sup.a represents ##STR14## R.sup.b represents ##STR15## R.sup.c represents ##STR16## R.sup.e represents ##STR17## and R.sup.f represents ##STR18## (wherein n and m independently represent 0 or 1;
• p, q and r independently represent 1 or 2;
• s represents 3 or 4;
• R.sup.1 and R.sup.2 are both hydrogen atoms or together represent an oxo group;
• R.sup.3 and R.sup.4 are both hydrogen atoms or together represent a carbon-carbon bond;
• R.sup.5 is hydrogen or an acyl group;
• each R.sup.6 and R.sup.7 independently represent a hydroxy group or an amino group, but are preferably hydroxy groups,
• R.sup.8 represents hydrogen;
• a C.sub.2-6 alkyl group;
• a C.sub.7-20 aralkyl group, which may carry one or more hydroxy, amino or methoxy substituents;
• or a metabolically labile S-protecting group;
• R.sup.9 represents hydrogen or a methyl group;
• and
• R.sup.10 represents a hydroxy or amino group, the residue of the amino acid glutamine or a peptide having an N-terminal glutamine unit).