Methods for the diagnosis of glaucoma
AssigneeThe Regents of the University of California
InventorsThai D. Nguyen, Jon R. Polansky, Weidong Huang
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Abstract
A glucocorticoid-induced protein, TIGR, that is produced by cells of the trabecular meshwork can be used to diagnose glaucoma. The TIGR protein, anti-TIGR antibodies, and TIGR encoding sequences also provide a diagnostic for glaucoma and its related diseases.
Claims16
A substantially purified nucleic acid molecule that encodes a mammalian Trabecular Meshwork Induced Glucocorticoid Response (TIGR) protein.
A substantially purified nucleic acid molecule that encodes a human Trabecular Meshwork Induced Glucocorticoid Response (TIGR) protein.
An isolated nucleic acid molecule that encodes a mammalian Trabecular Meshwork Induced Glucocorticoid Response (TIGR) protein.
An isolated nucleic acid molecule that encodes a human Trabecular Meshwork Induced Glucocorticoid Response (TIGR) protein.
A nucleic acid molecule comprising a substantially purified human Trabecular Meshwork Induced Glucocorticoid Response (TIGR) nucleic acid molecule of the sequence of SEQ ID NO:2 or SEQ ID NO:3.
A nucleic acid molecule comprising an isolated human Trabecular Meshwork Induced Glucocorticoid Response (TIGR) nucleic acid molecule of the sequence of SEQ ID NO:2 or SEQ ID NO:3.
Dependencies are inferred from the claim text.