Methods of diagnosing colorectal tumors and metastasis thereof
AssigneeThomas Jefferson University
InventorScott A. Waldman
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Abstract
In vitro methods of determining whether or not an individual has metastasized colorectal cancer cells are disclosed. In vitro methods of determining whether or not tumor cells are colorectal in origin are disclosed. In vitro kits for practicing the methods of the invention and to reagents and compositions useful to practice the methods, for example as components in such in vitro kits of the invention are provided. Methods of and kits and compositions for analyzing tissue samples from the colon tissue to evaluate the extent of metastasis of colorectal tumor cells are disclosed.
Claims8
An in vitro method of determining whether or not an individual has metastasized colorectal cancer cells comprising the steps of examining a sample of extraintestinal tissue and/or body fluids from an individual to determine whether ST receptor protein is being expressed by cells in said sample, wherein expression of ST receptor protein is indicative of the presence of metastasized colorectal cancer cells in said sample.
An in vitro method of determining whether or not a tumor cell is a colorectal tumor cell comprising the step of determining whether said tumor cell expresses ST receptor protein, wherein expression of ST receptor protein indicates that the tumor cell is a colorectal tumor cell.
Dependencies are inferred from the claim text.