Method of detecting viral infection in vaccinated animals
AssigneeThe Upjohn Company
InventorsLeonard E. Post, Darrell R. Thomsen
Life of this patent
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Abstract
Provided are methods for determining whether a vaccinated animal is uninfected or infected with a virulent wild-type virus. Methods, vaccines and viruses are disclosed that are useful to seratologically distinguish infected from uninfected animals in populations of animals vaccinated with a properly incapacitated virus lacking an antigen of the wild-type virus.
Claims20
A method for determining whether a vaccinated animal has been infected with a virulent wild-type virus comprising detecting the presence or absence of antibodies specific for a detectable antigen of said virulent wild-type virus in serum from said vaccinated animal, wherein said vaccinated animal has been vaccinated against said virulent wild-type virus with a vaccine that comprises a properly incapacitated virus lacking said detectable antigen of said wild-type virus which allows the serological distinction between vaccinated and infected animals.
Dependencies are inferred from the claim text.