Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia
AssigneeEndorecherche, Inc.
InventorFernand Labrie
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Abstract
A combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia in susceptible warm-blooded animals which comprises administering a combination of two or more compounds selected from the group consisting of an inhibitor of 5.alpha.-reductase activity, an antiestrogen, an inhibitor of aromatase activity, an inhibitor of 17.beta.-hydroxysteroid dehydrogenase activity and, in some cases, an anti-androgen and/or an LHRH agonist. Pharmaceutical compositions useful for such treatment and pharmaceutical kits containing such compositions are disclosed.
Claims7
A method of treating benign prostatic hyperplasia in a human or other warm-blooded animal said treatment comprising systemic administration to a patient in need of such treatment of both an amount of a 5.alpha.-reductase inhibitor and of a compound that binds and blocks access to androgen receptors effective to decrease prostate size, said administration being in combination with a pharmaceutically acceptable diluent or carrier.
Dependencies are inferred from the claim text.