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AssigneeBristol-Myers Squibb Company
InventorsJohn R. Wetterau, II, Daru Y. Sharp, Richard E. Gregg, Scott A. Biller, John K. Dickson, R. Michael Lawrence, John E. Lawson, Henry M. Holava, Richard A. Partyka
Estimating the term…
Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.
An isolated nucleic acid molecule consisting of an MTP nucleotide sequence, wherein the MTP nucleotide sequence encodes the high molecular weight subunit of microsomal triglyceride transfer protein.
An expression vector comprising an MTP nucleotide sequence, wherein the MTP nucleotide sequence encodes the high molecular weight subunit of microsomal triglyceride transfer protein.
A method for detecting a nucleic acid having an MTP nucleotide sequence, which comprises:
Dependencies are inferred from the claim text.