Method for preventing onset of hypertension employing a cholesterol lowering drug
AssigneeE. R. Squibb & Sons, Inc.
InventorsWerner Tschollar, Cary S. Yonce, James L. Bergey, James C. Kawano
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Abstract
A method is provided for preventing or reducing the risk of hypertension in normotensive patients having insulin resistance by administering a cholesterol lowering drug, such as pravastatin, alone or in combination with an ACE inhibitor, especially one containing a mercapto moiety, such as captopril or zofenopril.
Claims14
A method for treating a normotensive mammalian species having insulin resistance to inhibit hypertension, which comprises administering to a mammalian species in need of such treatment an effective amount of a cholesterol lowering drug which is a fibric acid derivative, probucol, dextrothyroxine or its sodium salt, colestipol or its hydrochloride, cholestyramine, nicotinic acid, neomycin, p-aminosalicylic acid or aspirin.
A method for treating a normotensive mammalian species having insulin resistance to inhibit hypertension, which comprises administering to a normotensive mammalian species in need of such treatment a combination of an effective amount of cholesterol lowering drug which is a fibric acid derivative, probucol, dextrothyroxine or its sodium salt, colestipol or its hydrochloride, cholestyramine, nicotinic acid, neomycin, p-aminosalicyclic acid or aspirin, and an effective amount of an angiotensin converting enzyme inhibitor.
Dependencies are inferred from the claim text.