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US 5,593,658 AGranted
Medical compositions
AssigneeThe General Hospital Corporation
InventorsAlexei A. Bogdanov, Thomas J. Brady
Life of this patent
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Abstract
A biocompatible medical composition including a polymeric carrier, a protective chain linked to the polymeric carrier, and a reporter group linked to the carrier or to the carrier and the protective chain. The invention also relates to a method of treating a disease in a patient by administering to the patient a therapeutically effective amount of the composition, and may include scanning the patient using an imaging technique which can detect the reporter group to obtain a visible image of the distribution of the composition.
Claims32
A biocompatible medical composition comprising:
- a non-polysaccharide polymeric carrier;
- a plurality of protective chains linked to said polymeric carrier, wherein each protective chain is at least 500 Daltons;
- and
- a reporter group linked to said carrier and not linked to said protective chain, wherein said reporter group is a complexone or a therapeutic agent, and both said carrier and said reporter group are protected by said protective chains from contact with macromolecules other than in said composition.
1 more element
Dependencies are inferred from the claim text.