Back to results
US 5,591,714 AGranted
Derivatives of A82846
AssigneeEli Lilly and Company
InventorsRamakrishnan Nagarajan, Amelia A. Schabel
Life of this patent
Estimating the term…
Abstract
New N-alkyl and N-acyl derivatives of A82846A, A82846B, A82846C and PA-42867-A are provided. The new glycopeptide derivatives are useful for the treatment of susceptible bacterial infections, especially infections due to Gram-positive microorganisms.
Claims32
A compound of the formula I ##STR11## R.sub.2 is C.sub.8 -C.sub.12 alkyl or a group of formula ##STR12## wherein n is 1 to 3;
- R.sub.4 is hydrogen, halo, C.sub.1 -C.sub.8 alkyl, or C.sub.1 -C.sub.8 alkoxy;
- m is 2 or 3 and r=3-m;
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.