Generation of neural precursor cell lines
AssigneeAmrad Corporation Limited
InventorsOra Bernard, Perry F. Bartlett
Life of this patent
Estimating the term…
Abstract
A method for the in vitro production of lines of immortalized neural precursor cells, including cell lines having neuronal and/or glial cell characteristics, comprises the step of infecting neuroepithelium or neural crest cells with a retroviral vector carrying a member of the myc family of oncogenes.
Claims12
An cell line comprising mammalian neuroepithelial or neural crest cells which have been infected with a retroviral vector carrying a c-myc or N-myc oncogene and in which said c-myc or N-myc gene is expressed.
A method for the in vitro production of immortalized mammalian neural precursor cells which comprises infecting mammalian neuroepithelium or neural crest cells with a retroviral vector carrying a c-myc or N-myc oncogene to provide infected cells, wherein said neuroepithelium or neural crest cells are capable of being infected by said retroviral vector, and under conditions whereby the c-myc or N-myc gene is expressed in said infected cells.
Dependencies are inferred from the claim text.