Broadly reactive opsonic antibodies that react with common staphylococcal antigens
AssigneeU.S. Government
InventorGerald W. Fischer
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Abstract
The invention relates to the identification, making, and isolation of immunoglobulin and antigen that is useful to prevent, diagnose, or treat Staphylococcus infections. The invention further relates to an in vivo animal model for testing the efficacy of pharmaceutical compositions, including the pharmaceutical compositions of immunoglobulin and isolated antigen described herein.
Claims7
An antigen preparation isolated from Staphylococcus epidermidis strain Hay ATCC 55133, wherein said preparation generates broadly reactive opsonic antibody which specifically reacts in an assay with Staphylococcus epidermidis serotypes I, II and III, and which exhibits opsonic activity greater than 70%.
A purified culture of Staphylococcus organisms, comprising Staphylococcus epidermidis strain Hay ATCC 55133.
Dependencies are inferred from the claim text.