Infection resistant medical devices
AssigneeThe Trustees of Columbia University in the City of New York
InventorsShanta Modak, Lester Sampath
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Abstract
The present invention provides for medical devices which are antiinfective as a result of antiinfective agents impregnated onto their surfaces and/or antiinfective activity incorporated into their access sites. It is based, at least in part, on the discovery that certain combinations of antimicrobial agents and solvents change the surface characteristics of polymeric medical devices, thereby facilitating the retention of antimicrobial agents. It is further based on the discovery that the incorporation of antiinfective polymeric inserts into the access site of a medical device provides substantially improved antiinfective activity.
Claims5
An injection port comprising an antiinfective insert selected from the group consisting of an antiinfective disc and an antiinfective ring, wherein the antiinfective disc or antiifective ring is comprised of a ploymer which has been impregnated, at its surface, with an antiifective agent.
Dependencies are inferred from the claim text.