Delivery of controlled-release systems(s)
AssigneeFuisz Technologies Ltd.
InventorsGarry L. Myers, Gerald E. Battist, Richard C. Fuisz
Life of this patent
Estimating the term…
Abstract
The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix and a controlled-release system, either molding or compacting a unit dosage form and curing the shearform matrix. The controlled-release systems used in the present invention include instantaneous release components, delayed release components, sustained release components, and combinations thereof.
Claims11
A method of preparing quick dissolve comestible units having a controlled-release system comprising:
- subjecting a feedstock which contains a carrier material to flash-flow processing to provide uncured shearform matrix;
- chopping said uncured shearform matrix;
- mixing said chopped uncured shearform matrix and a controlled-release system comprising a composition for making an active ingredient available to a host biological system with components selected from the group consisting of an instantaneous release component, a delayed released component, a sustained release component, and combinations thereof;
- molding the mixture of uncured shearform matrix and controlled-release system resulting from the previous step to provide a unit dosage form which has bridging between crystallized matrix material upon curing;
- and
- curing said shearform matrix to produce a stable structure.
Dependencies are inferred from the claim text.