Drug reconstitution and administration system

A drug reconstitution and administration system comprising:

• a container for containing a medicament having an open mouth, a thread formation generally at said mouth, and a removable stopper for closing said mouth;
• a syringe assembly including a barrel having an open end and a generally closed end defining a flow passage, and a plunger slidably positioned in said barrel and extending from said open end, said plunger defining with said barrel an internal chamber in fluid communication with said flow passage;
• and
• a mixing adapter assembly for mixing a liquid in said syringe assembly with the medicament in said container, said adapter assembly including a generally cylindrical outer sleeve having a thread formation at one end thereof for threaded connection with the thread formation of said container so that said stopper and said container mouth can be positioned in said one end of said outer sleeve,
• said adapter assembly further including a generally cylindrical inner sleeve slidably positioned in said outer sleeve in sealing engagement therewith, said inner sleeve having a generally closed end defining a flow port and an open end, said inner sleeve having an inside diameter larger than an outside diameter of the barrel of said syringe assembly, said inner sleeve defining with said outer sleeve an expandable mixing chamber within said outer sleeve, said inner sleeve including removal means at said flow port engageable with said stopper of said container when said container mouth is threadably connected with said outer sleeve,
• said inner sleeve and said barrel of said syringe assembly respectively comprising mating thread formations for detachably connecting said inner sleeve and said barrel to connect said flow passage and said flow port in fluid communication, so that said syringe assembly is positionable generally within the open end of said inner sleeve and threadably connected thereto, and a liquid in said internal chamber of said syringe assembly can be caused to flow through said flow passage and said flow port into said expandable mixing chamber as the inner sleeve slides outwardly of said outer sleeve to effect removal of said stopper from said container so that the liquid can be mixed with medicament from said container to form a mixture, said mixture thereafter being caused to flow from said mixing chamber into said internal chamber of said syringe assembly by movement of said inner sleeve inwardly of said outer sleeve and movement of said plunger outwardly of said outer barrel for subsequent administration of said mixture from syringe assembly after detachment of said barrel from said inner sleeve.