US 5,565,213 A · Stable liposome aqueous suspension

Abstract

A liposome aqueous suspension containing taurine and benzalkonium chloride is disclosed. The liposome aqueous suspension undergoes no precipitation, agglomeration or change in particle size even when preserved at 40.degree. C. for 6 months and is inhibited from lyso-phospholipid formation.

Claims1

Dependent claims

A liposome aqueous suspension containing taurine in the liposomes and the external aqueous phase, which contains 0.5 to 5.0% by weight of taurine based on the total amount of the liposome preparation and 0.05 to 20 mol %, based on the membrane component of the liposomes, of benzalkonium chloride in the membranes of the liposomes and the external aqueous phase.

Dependencies are inferred from the claim text.

Facts

Application

08/318,750Filed 21 Oct 1994

Granted

15 Oct 1996

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

A61K 9/1272
Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers: comprising non-phosphatidyl surfactants as…
A61K 9/127
Dispersions; Emulsions: synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
B01J 13/0021
Preparation of sols: containing a solid organic phase
Y10T 428/2984
Particulate matter [e.g., sphere, flake, etc.]: microcapsule with fluid core [includes liposome]

Abstract

Claims1

Dependent claims

Dependencies are inferred from the claim text.

Stable liposome aqueous suspension

Life of this patent

Abstract

Claims1

Stable liposome aqueous suspension

Life of this patent

Abstract

Claims1